INT296950

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.94
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck) plasma membrane (Tacr1)
response to stress (Tacr1) cytoplasm (Tacr1) signal transducer activity (Tacr1)
Anatomy Link Frequency
dorsal horn 2
Tacr1 (Rattus norvegicus)
Cck (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 33 100.00 Very High Very High Very High
Dorsal horn 26 99.20 Very High Very High Very High
allodynia 7 99.04 Very High Very High Very High
Cold hyperalgesia 5 98.48 Very High Very High Very High
Neuropathic pain 26 89.32 High High
Inflammation 5 80.20 Quite High
cytokine 1 72.68 Quite High
Inflammatory mediators 1 69.40 Quite High
withdrawal 26 65.80 Quite High
Thermal hyperalgesia 2 57.28 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 43 99.04 Very High Very High Very High
Hyperalgesia 12 98.48 Very High Very High Very High
INFLAMMATION 6 80.20 Quite High
Wallerian Degeneration 1 53.20 Quite High
Injury 10 50.00 Quite Low
Inflammatory Pain 1 49.48 Quite Low
Nociception 10 40.88 Quite Low
Syndrome 2 34.36 Quite Low
Pain 14 5.00 Very Low Very Low Very Low
Nervous System Injury 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Persistently elevated NK-1R and decreased CCK expression in the superficial dorsal horn correlate with the abnormal cold sensitivity.
NK-1R Negative_regulation (decreased) of Gene_expression (expression) of CCK in dorsal horn associated with dorsal horn and cholecystokinin
1) Confidence 0.30 Published 2010 Journal Mol Pain Section Body Doc Link PMC2825192 Disease Relevance 0.94 Pain Relevance 1.11

General Comments

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