INT297113

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.87
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 2
TEX33 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 19 100.00 Very High Very High Very High
Peripheral nervous system 10 95.48 Very High Very High Very High
Inflammation 26 89.64 High High
Central nervous system 8 71.04 Quite High
Demyelination 13 26.84 Quite Low
Sciatic nerve 7 5.00 Very Low Very Low Very Low
sodium channel 6 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 19 100.00 Very High Very High Very High
Guillain-barre Syndrome 24 98.72 Very High Very High Very High
Syndrome 62 97.92 Very High Very High Very High
Immunization 6 97.12 Very High Very High Very High
Neuropathy 32 92.68 High High
Disease 46 91.16 High High
Demyelinating Disease 28 90.20 High High
INFLAMMATION 26 89.64 High High
Chronic Inflammatory Demyelinating Polyradiculoneuropathy 10 89.64 High High
Autoimmune Disease 8 86.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EAN can be transferred to animals by T cells sensitized to peripheral nerve proteins such as P2 protein.
Positive_regulation (transferred) of Gene_expression (transferred) of EAN in T cells associated with neuritis
1) Confidence 0.01 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3010740 Disease Relevance 2.37 Pain Relevance 0.42
Active EAN and "adoptive-transfer EAN", for example, reflect the Th1-dominated stages of GBS [12,13] whereas immunisation with a single large dose of PNS myelin or galactocerebrosides in complete Freund's adjuvants lead to a chronic progressive or relapsing disease course, compatible with human CIDP [14].
Positive_regulation (transfer) of Gene_expression (transfer) of EAN associated with chronic inflammatory demyelinating polyradiculoneuropathy, peripheral nervous system, syndrome, immunization, disease and neuritis
2) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2825213 Disease Relevance 1.49 Pain Relevance 0.72

General Comments

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