INT297203

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Context Info
Confidence 0.55
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ppp3ca) mitochondrion (Ppp3ca) nucleus (Ppp3ca)
enzyme binding (Ppp3ca) response to stress (Ppp3ca) cytoplasm (Ppp3ca)
Anatomy Link Frequency
heart 1
Ppp3ca (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 16 33.76 Quite Low
agonist 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 12 99.60 Very High Very High Very High
Targeted Disruption 36 80.48 Quite High
Coronary Heart Disease 4 54.76 Quite High
Congenital Anomalies 4 41.36 Quite Low
Heart Disease 8 38.64 Quite Low
Cardiovascular Disorder Under Development 8 34.40 Quite Low
Stress 8 26.24 Quite Low
Arrhythmia Under Development 52 5.00 Very Low Very Low Very Low
Hyperplasia 20 5.00 Very Low Very Low Very Low
Sudden Death 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, activated CnA expression was essentially unable to significantly induce NFAT-luciferase activity in CnB1-deleted MEFs (Fig. 2D).
Gene_expression (expression) of CnA
1) Confidence 0.55 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.22 Pain Relevance 0
An adenovirus expressing Cre recombinase was used to delete CnB1 from MEFs containing the LoxP-targeted homozygous alleles, which reduced CnA and CnB1 protein levels by ?
Gene_expression (levels) of CnA
2) Confidence 0.48 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.24 Pain Relevance 0
The mammalian heart only expresses CnA?
Gene_expression (expresses) of CnA in heart
3) Confidence 0.43 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.05 Pain Relevance 0
Simultaneous infection with an adenovirus expressing the activated (truncated) form of CnA showed relatively stable expression even in the absence of CnB1 (Fig. 2C).
Gene_expression (expressing) of CnA associated with infection
4) Confidence 0.41 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.23 Pain Relevance 0

General Comments

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