INT297210

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nfatc1, Myoz1) DNA binding (Nfatc1) cytoplasm (Nfatc1)
Anatomy Link Frequency
heart 1
Nfatc1 (Mus musculus)
Myoz1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 4 81.72 Quite High
agonist 2 65.44 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arrhythmia Under Development 13 95.12 Very High Very High Very High
Apoptosis 2 86.16 High High
Fibrosis 3 81.72 Quite High
Sudden Death 4 69.28 Quite High
Death 3 61.16 Quite High
Embryonic Lethality 1 28.04 Quite Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Hyperplasia 5 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is not clear whether loss of NFAT activity in the heart is directly responsible for this effect or one of many other targets of calcineurin that are NFAT-independent.
NFAT-independent Regulation (targets) of calcineurin in heart
1) Confidence 0.06 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.51 Pain Relevance 0.07

General Comments

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