INT297214

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2) extracellular space (Car2) lyase activity (Car2)
nucleus (Myoz1) cytoplasm (Car2)
Anatomy Link Frequency
cardiac myocyte 4
Myoz1 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 8 56.96 Quite High
agonist 4 40.68 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arrhythmia Under Development 26 70.36 Quite High
Apoptosis 4 61.40 Quite High
Fibrosis 6 56.96 Quite High
Sudden Death 8 44.52 Quite Low
Death 6 36.40 Quite Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Hyperplasia 10 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Heart Disease 4 5.00 Very Low Very Low Very Low
Heart Rate Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, calcineurin also directly up-regulates L-type Ca2+ channel activity in cardiac myocytes, again suggesting that calcineurin signaling is important for both expression and activity of the Ca2+-handling machinery in a cardiac myocyte (47).
calcineurin Regulation (important) of Gene_expression (expression) of Ca2 in cardiac myocyte
1) Confidence 0.03 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.25 Pain Relevance 0.03
Finally, calcineurin also directly up-regulates L-type Ca2+ channel activity in cardiac myocytes, again suggesting that calcineurin signaling is important for both expression and activity of the Ca2+-handling machinery in a cardiac myocyte (47).
calcineurin Regulation (important) of Gene_expression (expression) of Ca2 in cardiac myocyte
2) Confidence 0.03 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.25 Pain Relevance 0.03

General Comments

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