INT297219

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Abcc8) plasma membrane (Abcc8) transmembrane transport (Abcc8)
Anatomy Link Frequency
neuronal 1
proximal 1
Abcc8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
withdrawal 4 98.28 Very High Very High Very High
Spinal nerve ligature 46 90.68 High High
Pain 18 82.96 Quite High
Hyperalgesia 12 82.64 Quite High
Neuropathic pain 16 66.88 Quite High
Peripheral nerve injury 2 34.68 Quite Low
Neurotransmitter 6 29.68 Quite Low
anesthesia 8 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
nociceptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 8 99.12 Very High Very High Very High
Hyperalgesia 14 89.68 High High
Charcot Marie Tooth Disease 4 86.60 High High
Peripheral Neuropathy 2 85.40 High High
Nervous System Injury 18 82.32 Quite High
Neuropathic Pain 18 66.88 Quite High
Pain 2 33.48 Quite Low
Hypoxia 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our observations of decreased SUR1 at these sites after injury suggests that withdrawal of KATP channel activity may support neuronal regeneration.
Negative_regulation (decreased) of SUR1 in neuronal associated with injury and withdrawal
1) Confidence 0.54 Published 2010 Journal Mol Pain Section Body Doc Link PMC2825500 Disease Relevance 0.91 Pain Relevance 0.61
In DRG and dorsal roots proximal to axotomy SLI were smaller and showed decreased SUR1 immunofluorescence.


Negative_regulation (decreased) of SUR1 in proximal
2) Confidence 0.40 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2825500 Disease Relevance 0.17 Pain Relevance 0.32

General Comments

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