INT297240

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.38
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dendrite 1
immune system 1
Gsi1 (Mus musculus)
Pain Link Frequency Relevance Heat
Thalamus 81 91.52 High High
Hippocampus 18 35.36 Quite Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress Incontinence 105 100.00 Very High Very High Very High
Disease 69 100.00 Very High Very High Very High
Toxicity 9 98.04 Very High Very High Very High
Scrapie 69 94.60 High High
Infection 6 82.88 Quite High
Creutzfeldt Jakob Disease 108 53.36 Quite High
Death 21 5.00 Very Low Very Low Very Low
Sprains And Strains 15 5.00 Very Low Very Low Very Low
Kuru 6 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Like many GSI's designed to treat Alzheimer's disease, it produces severe gastrointestinal tract and immune system toxicity; therefore, it is not used clinically.
Gene_expression (produces) of GSI in immune system associated with toxicity, stress incontinence and disease
1) Confidence 0.09 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2825502 Disease Relevance 0.76 Pain Relevance 0.03
It was our belief that any reduction of PrPSc in brain caused by Qa would be additive to the GSI effect in terms of reducing NICD formation and dendrite degeneration.
Gene_expression (effect) of GSI in dendrite associated with stress incontinence
2) Confidence 0.09 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2825502 Disease Relevance 1.05 Pain Relevance 0.08
This suggests that Qa was able to modulate the effect of GSI.
Gene_expression (effect) of GSI associated with stress incontinence
3) Confidence 0.09 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2825502 Disease Relevance 0.56 Pain Relevance 0

General Comments

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