INT297293

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.79
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Hyou1) response to stress (Hyou1)
Anatomy Link Frequency
epithelial cells 2
Hyou1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 24 86.16 High High
cytokine 93 63.92 Quite High
chemokine 72 62.80 Quite High
Inflammation 144 59.44 Quite High
ischemia 78 24.96 Low Low
Inflammatory mediators 9 5.00 Very Low Very Low Very Low
antagonist 9 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 24 99.52 Very High Very High Very High
Hypoxia 6 99.04 Very High Very High Very High
Injury 489 98.72 Very High Very High Very High
Targeted Disruption 33 92.88 High High
Death 9 92.28 High High
INFLAMMATION 180 86.16 High High
Necrosis 3 44.08 Quite Low
Cancer 6 43.72 Quite Low
Cv Unclassified Under Development 78 24.96 Low Low
Adhesions 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The oxygen-regulated protein (ORP150) is an inducible ER chaperone.
Positive_regulation (inducible) of Gene_expression (chaperone) of ORP150
1) Confidence 0.34 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 1.58 Pain Relevance 0.13
The oxygen-regulated protein (ORP150) is an inducible ER chaperone.
Positive_regulation (inducible) of Gene_expression (chaperone) of oxygen-regulated protein
2) Confidence 0.34 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 1.59 Pain Relevance 0.13
Renal tubular epithelial cells transfected with ORP150 were protected against hypoxic injury whereas inhibition of ORP150 made cells more susceptible to hypoxic injury [138].
Positive_regulation (transfected) of Gene_expression (transfected) of ORP150 in epithelial cells associated with hypoxia and injury
3) Confidence 0.30 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 1.61 Pain Relevance 0.14

General Comments

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