INT297311

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Casp1, Il18) extracellular region (Casp1, Il18) intracellular (Casp1)
protein complex (Casp1) peptidase activity (Casp1) extracellular space (Il18)
Anatomy Link Frequency
lymphocytes 1
Casp1 (Mus musculus)
Il18 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 31 98.64 Very High Very High Very High
chemokine 24 98.08 Very High Very High Very High
antagonist 3 84.56 Quite High
Inflammation 48 72.48 Quite High
Inflammatory response 8 54.28 Quite High
ischemia 26 33.36 Quite Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 163 99.92 Very High Very High Very High
INFLAMMATION 60 72.48 Quite High
Acute Renal Failure 3 63.04 Quite High
Targeted Disruption 11 51.92 Quite High
Apoptosis 3 49.36 Quite Low
Reperfusion Injury 4 34.12 Quite Low
Cv Unclassified Under Development 26 33.36 Quite Low
Fibrosis 2 32.56 Quite Low
Adhesions 12 5.00 Very Low Very Low Very Low
Renal Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of IL-18 by caspase-1 results in production of several cytokines and chemokines, activation of T helper cells, and proliferation of lymphocytes.
caspase-1 Positive_regulation (Activation) of IL-18 in lymphocytes associated with chemokine and cytokine
1) Confidence 0.09 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 1.02 Pain Relevance 0.55

General Comments

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