INT297331

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Apoe, Il6) extracellular region (Apoe, Il6) lipid binding (Apoe)
transport (Apoe) aging (Apoe) Golgi apparatus (Apoe)
Apoe (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
Peripheral nervous system 5 99.68 Very High Very High Very High
Neuritis 24 82.16 Quite High
cytokine 13 77.32 Quite High
Inflammation 12 43.24 Quite Low
Sciatic nerve 1 30.96 Quite Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 24 82.16 Quite High
Targeted Disruption 19 70.16 Quite High
Nervous System Injury 1 62.64 Quite High
Syndrome 19 50.00 Quite Low
Disorder Of Lipid Metabolism 6 50.00 Quite Low
Disease 7 46.28 Quite Low
INFLAMMATION 13 43.24 Quite Low
Autoimmune Disease 7 40.60 Quite Low
Multiple Sclerosis 6 5.00 Very Low Very Low Very Low
Immunization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ApoE-deficient mice were observed to reduce the expression of intracellular IL-6 accompanied with higher levels of MHC II and CD 40 expression on SCs.
ApoE Negative_regulation (reduce) of Gene_expression (expression) of IL-6
1) Confidence 0.14 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2825561 Disease Relevance 0.61 Pain Relevance 0.57

General Comments

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