INT297347

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.33 Pain Relevance 0

cytosol (MEFV) cytoskeleton (MEFV) nucleus (MEFV) intracellular (MEFV) cytoplasm (MEFV)

MEFV (Homo sapiens) SAA@ (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 3 22.64 Arthritis 3 5.00 Pain 2 5.00 abdominal pain 2 5.00

Disease Link Frequency Relevance Heat Familial Mediterranean Fever 62 100.00 Amyloidosis 3 98.68 Spirochete Infection 3 95.56 Disease 27 90.76 Fever 32 84.52 Syndrome 1 73.84 Tumor Necrosis Factor Receptor-associated Periodic Syndrome 1 71.84 INFLAMMATION 3 22.64 Arthritis 3 5.00 Pain 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Third, previous studies in FMF patients showed that the presence of modifying alleles in MICA and SAA are associated with a severe FMF phenotype and susceptibility to amyloidosis [4, 50].

FMF Binding (associated) of SAA associated with amyloidosis and familial mediterranean fever

1) Confidence 0.03 Published 2010 Journal The Open Rheumatology Journal Section Body Doc Link PMC2825617 Disease Relevance 1.33 Pain Relevance 0

General Comments

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