INT297377

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.25
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (PPARA, Rxra) nucleus (PPARA, Rxra) nucleoplasm (PPARA)
small molecule metabolic process (PPARA) enzyme binding (Rxra) lipid metabolic process (PPARA)
PPARA (Homo sapiens)
Rxra (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 15 63.88 Quite High
Inflammation 21 34.20 Quite Low
agonist 99 5.00 Very Low Very Low Very Low
cINOD 21 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 6 73.44 Quite High
INFLAMMATION 36 63.48 Quite High
Obesity 51 61.00 Quite High
Familial Partial Lipodystrophy 3 54.48 Quite High
Metabolic Syndrome 3 48.08 Quite Low
Dyslipidemia /

Combined Dyslipidemia

3 45.12 Quite Low
Wound Healing 3 43.68 Quite Low
Liver Cancer 6 42.72 Quite Low
Hepatomegaly 3 41.08 Quite Low
Syndrome 3 36.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RXR is a promiscuous receptor and able to heterodimerize with RAR, PPAR, VDR, TR, and orphan receptors.
PPAR Binding (heterodimerize) of RXR
1) Confidence 0.02 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.20 Pain Relevance 0.03
A unique association with PPAR and RXR is the direct repeat responsive elements (DR) and the PPAR response elements (PPRE) associated with the heterodimer.
PPAR Binding (association) of RXR
2) Confidence 0.02 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0 Pain Relevance 0
A unique association with PPAR and RXR is the direct repeat responsive elements (DR) and the PPAR response elements (PPRE) associated with the heterodimer.
PPAR Binding (association) of RXR
3) Confidence 0.02 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.05 Pain Relevance 0

General Comments

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