INT297454

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) plasma membrane (Ntrk1) kinase activity (Ntrk1)
cytoplasm (Ntrk1)
Ntrk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 44 99.78 Very High Very High Very High
withdrawal 3 50.00 Quite Low
Neurotransmitter 1 12.48 Low Low
Hippocampus 7 5.00 Very Low Very Low Very Low
GABAergic 3 5.00 Very Low Very Low Very Low
Intracerebroventricular 2 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 64.04 Quite High
Death 12 56.72 Quite High
Apoptosis 11 17.36 Low Low
Nervous System Injury 1 6.00 Low Low
Disease 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 7 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 1 5.00 Very Low Very Low Very Low
Down Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that the lack of response to NGF is due to down-regulation of TrkA.
Negative_regulation (down) of Negative_regulation (regulation) of TrkA associated with nerve growth factor
1) Confidence 0.09 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2826326 Disease Relevance 0.23 Pain Relevance 0.41

General Comments

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