INT297468

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.63
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 1.85
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasmic membrane-bounded vesicle (Kdr) plasma membrane (Kdr) nucleus (Kdr)
cytoplasm (Kdr)
Anatomy Link Frequency
retinas 1
Kdr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
endometriosis 69 97.40 Very High Very High Very High
metalloproteinase 5 50.00 Quite Low
corticosteroid 28 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
imagery 12 5.00 Very Low Very Low Very Low
anesthesia 11 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 99 97.40 Very High Very High Very High
Diabetes Mellitus 220 96.88 Very High Very High Very High
Pituitary Cancer 16 91.12 High High
Ganglion Cysts 8 77.20 Quite High
Cancer 81 50.00 Quite Low
Prolactinoma 2 50.00 Quite Low
Apoptosis 26 20.96 Low Low
Diabetic Macular Edema 84 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 28 5.00 Very Low Very Low Very Low
Blindness 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vegf-a and Flk-1 transcription was significantly downregulated 2.9- and 2.0-fold, respectively (PVegf-a = 0.030 and PFlk-1 = 0.028); however, Flt-1 was significantly upregulated 1.3-fold (PFlt-1 = 0.002) with IVTA treatment (Fig. 1B).
Transcription (transcription) of Flk-1
1) Confidence 0.63 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.30 Pain Relevance 0
There was no statistically significant difference in the transcription of Vegf-a and Flk-1 or Flt-1 between sham-treated and IVTA-treated nondiabetic groups (PVegf-a = 0.519, PFlk-1 = 0.679, and PFlt-1 = 0.909) (Fig. 1C).


Transcription (transcription) of Flk-1
2) Confidence 0.63 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.40 Pain Relevance 0
Expression of mRNA encoding for VEGF, Flk-1 and MMP-9
Transcription (encoding) of Flk-1
3) Confidence 0.61 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2826344 Disease Relevance 0.64 Pain Relevance 0.14
Retinal gene transcription of Vegf-a, Flk-1, and Flt-1.
Transcription (transcription) of Flk-1
4) Confidence 0.47 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.07 Pain Relevance 0
Transcription of Vegf-a and Flk-1 was significantly increased by 2.5- and 1.8-fold (PVegf-a = 0.001 and PFlk-1 = 0.031), respectively, but Flt-1 was downregulated 4.3-fold (PFlt-1 = 0.005) in sham-treated diabetic retinas compared with sham-treated nondiabetic retinas (Fig. 1A).
Transcription (Transcription) of Flk-1 in retinas associated with diabetes mellitus
5) Confidence 0.47 Published 2008 Journal Diabetes Section Body Doc Link PMC2836241 Disease Relevance 0.26 Pain Relevance 0
On the other hand, the expression level of Flk-1 mRNA was decreased significantly in the E2+G6-31 group compared to the E2 group (Fig. 5K).


Transcription (expression) of Flk-1
6) Confidence 0.29 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875861 Disease Relevance 0.09 Pain Relevance 0
On the other hand, the expression level of Flk-1 mRNA was decreased significantly in the E2+G6-31 group compared to the E2 group (Fig. 5K).


Transcription (level) of Flk-1
7) Confidence 0.29 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875861 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox