INT297488

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Itpr3) endoplasmic reticulum (Itpr3) nucleolus (Itpr3)
nucleus (Itpr3) transmembrane transport (Itpr3) cytoplasm (Itpr3)
Anatomy Link Frequency
spinal 4
Itpr3 (Rattus norvegicus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 136 100.00 Very High Very High Very High
antagonist 20 100.00 Very High Very High Very High
agonist 16 92.88 High High
Dorsal horn 6 90.24 High High
Hippocampus 6 89.84 High High
Spinal cord 28 87.08 High High
Sciatic nerve 16 86.32 High High
spinal dorsal horn 26 84.56 Quite High
c fibre 26 82.84 Quite High
Dorsal horn neuron 10 82.32 Quite High
Disease Link Frequency Relevance Heat
Low Back Pain 10 77.20 Quite High
Nociception 6 75.00 Quite High
Ganglion Cysts 38 66.96 Quite High
Pain 10 28.68 Quite Low
Neuropathic Pain 2 20.36 Low Low
Hyperalgesia 4 19.80 Low Low
Li-fraumeni Syndrome 8 5.00 Very Low Very Low Very Low
Overdose 4 5.00 Very Low Very Low Very Low
Opiate Addiction 4 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Involvement of RyR, but not IP3R, in the induction of spinal LTP
IP3R Regulation (Involvement) of Positive_regulation (induction) of LTP in spinal associated with long-term potentiation
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2826347 Disease Relevance 0.06 Pain Relevance 0.68
Perfusion of RyR antagonists blocked the induction of LT stimulation-evoked spinal LTP, while Ins(1,4,5)P3 receptor (IP3R) antagonist had no significant effect on LTP induction.
IP3R Neg (no) Regulation (effect) of Positive_regulation (induction) of LTP in spinal associated with antagonist and long-term potentiation
2) Confidence 0.01 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2826347 Disease Relevance 0.40 Pain Relevance 1.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox