INT297558

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SRA1) transport (APOL1) DNA binding (SRA1)
cytoplasm (SRA1) lipid binding (APOL1) cell proliferation (SRA1)
APOL1 (Homo sapiens)
SRA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 14.48 Low Low
cytokine 14 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
African Trypanosomiasis 22 97.20 Very High Very High Very High
Targeted Disruption 3 93.48 High High
Trypanosomiasis 31 87.40 High High
Communicable Diseases 1 60.80 Quite High
INFLAMMATION 13 14.48 Low Low
Parasitic Infection 3 14.08 Low Low
Infection 53 11.28 Low Low
Disease 26 5.00 Very Low Very Low Very Low
Parasitemia 14 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, it has been shown that the full length baboon APOL1 (which does not interact with SRA) is protective against both the animal-infective and human-infective T. rhodesiense in an experimental mouse model, and, as such, it has been suggested to create transgenic livestock that would be resistant to animal and human-infective trypanosomes, which is envisaged to result in the reduction of the livestock trypanosomiasis and zoonotic transmission of human infective trypanosomes [119].
APOL1 Neg (not) Binding (interact) of SRA associated with targeted disruption and trypanosomiasis
1) Confidence 0.22 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2826769 Disease Relevance 0.56 Pain Relevance 0

General Comments

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