INT297680

Context Info Confidence 0.62 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.03

cytosol (Actb) cytoskeleton (Actb) protein complex (Actb) cytoplasm (Actb)

Anatomy Link Frequency kidney 1 Actb (Mus musculus)

Pain Link Frequency Relevance Heat imagery 5 57.60 cytokine 50 5.00 Inflammation 15 5.00 anesthesia 6 5.00 alcohol 6 5.00 isoflurane 2 5.00 ischemia 1 5.00 Pain 1 5.00 Buprenorphine 1 5.00 local anesthetic 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 18 26.52 Rhabdomyolysis 5 13.48 Injury 26 12.44 Necrosis 84 12.16 INFLAMMATION 15 5.00 Chronic Renal Failure 3 5.00 Renal Disease 3 5.00 Death 1 5.00 Chromosome Aberrations 1 5.00 Reperfusion Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Both the luciferase gene and a human housekeeping gene ACTB (both expressed only in human cells) were present only in the injected kidney tissue, as confirmed by the absence of the both housekeeping ACTB and luciferase gene in non-injected kidneys (Figure 3D).

Neg (absence) Localization (absence) of ACTB in kidney

1) Confidence 0.62 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827539 Disease Relevance 0 Pain Relevance 0.03

General Comments

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