INT297714

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cbr1) plasma membrane (Cbr1) nucleus (Cbr1)
cytoplasm (Cbr1)
Cbr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 46 50.00 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 108 88.96 High High
Obesity 4 83.44 Quite High
Disease 34 77.80 Quite High
Apoptosis 68 50.00 Quite Low
INFLAMMATION 46 50.00 Quite Low
Lifespan 24 50.00 Quite Low
Aging 8 48.40 Quite Low
Diabetes Mellitus 2 41.76 Quite Low
Eating Disorder 4 21.48 Low Low
Motor Neuron Diseases 32 20.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This may indicate that the protective antioxidant response was incomplete (i.e. partial), and hence insufficient to mitigate the CR-induced increase in lipid peroxidative damage.
CR Spec (partial) Binding (mitigate) of
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827549 Disease Relevance 0.12 Pain Relevance 0
This finding is in line with studies showing an association of CR with increased levels of UCP3.
CR Binding (association) of
2) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827549 Disease Relevance 0.45 Pain Relevance 0

General Comments

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