INT297736

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.29
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ucp3) mitochondrion (Ucp3) oxidoreductase activity (Cbr1)
plasma membrane (Cbr1) nucleus (Cbr1) transmembrane transport (Ucp3)
Cbr1 (Mus musculus)
Ucp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 23 73.40 Quite High
Spinal cord 2 37.24 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 54 97.24 Very High Very High Very High
Motor Neuron Diseases 16 87.68 High High
Disease 17 86.56 High High
Lifespan 12 82.64 Quite High
Disease Progression 11 78.28 Quite High
Apoptosis 34 74.64 Quite High
INFLAMMATION 23 73.40 Quite High
Targeted Disruption 1 45.56 Quite Low
Neuromuscular Disease 1 34.04 Quite Low
Death 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we hypothesized that CR would: (a) increase antixodant enzymes (MnSOD and Cu/Zn-SOD) and UCP3 as a compensatory mechanism to counteract the increase in oxidative stress, (b) not affect catalase activity since this enzyme is resistant to changes in dietaty intake, (c) increase TNF-?
CR Positive_regulation (increase) of UCP3 associated with stress
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827549 Disease Relevance 1.29 Pain Relevance 0.07

General Comments

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