INT297737

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cbr1, Bax) nucleus (Cbr1, Bax) mitochondrion (Bax)
endoplasmic reticulum (Bax) intracellular (Bax) lipid binding (Bax)
Cbr1 (Mus musculus)
Bax (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 23 65.20 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 34 94.16 High High
Disease Progression 11 76.24 Quite High
INFLAMMATION 23 65.20 Quite High
Stress 54 59.28 Quite High
Lifespan 12 50.00 Quite Low
Disease 17 42.80 Quite Low
Shock 2 21.84 Low Low
Death 9 20.80 Low Low
Motor Neuron Diseases 16 5.00 Very Low Very Low Very Low
Body Weight 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we show that CR increases Bax protein content, with no difference in caspase 9 or cleaved caspase 9 levels in our diseased animal model, illustrating that not every component of the mitochondrial-mediated apoptotic pathway is necessarily affected by CR.
CR Positive_regulation (increases) of Bax protein associated with apoptosis
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827549 Disease Relevance 0.53 Pain Relevance 0.03

General Comments

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