INT297836

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.80
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ndp) extracellular region (Ndp)
Ndp (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 3 33.68 Quite Low
Neuropeptide 6 21.60 Low Low
member 8 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Substantia nigra 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 33 95.44 Very High Very High Very High
Starvation 69 94.56 High High
Intellectual Impairment 3 89.72 High High
Deafness 3 88.80 High High
Blindness 3 87.76 High High
Sprains And Strains 3 87.48 High High
Disease 6 84.68 Quite High
Syndrome 63 83.12 Quite High
Hyperphagia 24 73.32 Quite High
Failure To Thrive 12 71.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike in adult rodents, expression levels of Nanos2 and Pdk4 were increased, and those of Pgpep1, Ndp, Brms1l, Mett10d, and Snx1 were decreased after neonatal deprivation.
Negative_regulation (deprivation) of Ndp
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2827556 Disease Relevance 0.97 Pain Relevance 0
We found a modest decrease of Ndp transcripts in the hypothalami of deprived pups, without changes in Frizzled4 and Lrp5 transcript levels.
Negative_regulation (decrease) of Ndp
2) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827556 Disease Relevance 0.58 Pain Relevance 0
But we detected transcription changes in unexpected genes, Nanos2 and Pdk4, which are increased by roughly 2-fold and 1.5-fold respectively, and Ndp, Pgpep1, Brms1l, Mett10d and Snx1, which are reduced by 25–55% (Figure 2 and Table 1).


Negative_regulation (reduced) of Ndp
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827556 Disease Relevance 0.25 Pain Relevance 0

General Comments

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