INT297872

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ppargc1a) RNA binding (Ppargc1a) mitochondrion organization (Ppargc1a)
nucleus (Ppargc1a) DNA binding (Ppargc1a) transcription factor binding (Ppargc1a)
Anatomy Link Frequency
muscle 1
Ppargc1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 4 93.00 High High
fibrosis 18 68.96 Quite High
antagonist 5 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 80.00 Quite High
Immunization 15 75.12 Quite High
Fibrosis 14 68.96 Quite High
Hypertrophy 12 54.08 Quite High
Coronary Heart Disease 18 50.00 Quite Low
Autoimmune Disease 2 50.00 Quite Low
Body Weight 2 16.32 Low Low
Hypertension 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Myocardial Infarction 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Important components of the energy metabolism like muscle glycogen phosphorylase and the peroxisome proliferators-activated receptor-gamma, co-activator 1, alpha (Ppargc1a) a master regulator of metabolic function responsible for fatty acid uptake and oxidation and oxidative phosphorylation[10] were upregulated (Table 1).
Positive_regulation (upregulated) of Ppargc1a in muscle
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827566 Disease Relevance 0.58 Pain Relevance 0.17

General Comments

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