INT29788

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Context Info
Confidence 0.03
First Reported 1988
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.61
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (DNASE1L1) DNA binding (DNASE1L1) DNA metabolic process (DNASE1L1)
Anatomy Link Frequency
CSF 1
saliva 1
DNASE1L1 (Homo sapiens)
Pain Link Frequency Relevance Heat
methadone 5 99.04 Very High Very High Very High
Opioid 4 92.48 High High
antagonist 1 77.04 Quite High
Endogenous opioid 2 75.00 Quite High
addiction 2 67.96 Quite High
cytokine 1 19.60 Low Low
Inflammatory response 1 6.68 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 13 84.40 Quite High
Disease 9 83.92 Quite High
Injury 18 75.92 Quite High
Fracture Healing 32 68.76 Quite High
Osteoporosis 7 57.92 Quite High
Cancer 23 50.00 Quite Low
Pressure Volume 2 Under Development 4 23.40 Low Low
Hematoma 1 21.40 Low Low
Coagulation Disorder 1 17.80 Low Low
Vasculitis 1 7.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The source of this information-complexity is the large variety of DNAs, RNAs and proteins present in the saliva (Fig. 1).
Gene_expression (source) of DNAs in saliva
1) Confidence 0.03 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674305 Disease Relevance 0.23 Pain Relevance 0
During methadone maintenance and drug-free states, the addicts' levels of fraction I RRA endorphins in the CSF were higher than levels found in a normal control group.
Gene_expression (levels) of fraction I in CSF associated with methadone
2) Confidence 0.02 Published 1988 Journal Biol. Psychiatry Section Abstract Doc Link 2844315 Disease Relevance 0 Pain Relevance 0.99
This discovery led to the expression of complementary DNAs and recognization of BMP in the family of the transforming growth factor-?
Gene_expression (expression) of DNAs
3) Confidence 0.01 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721393 Disease Relevance 0.38 Pain Relevance 0

General Comments

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