INT297906

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Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.91
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Foxo3) nucleus (Foxo3) embryo development (Foxo3)
DNA binding (Foxo3) transcription factor binding (Foxo3) response to stress (Foxo3)
Anatomy Link Frequency
puncture 1
Foxo3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
halothane 2 85.88 High High
anesthesia 9 84.84 Quite High
Immobilon 2 61.48 Quite High
Inflammatory response 5 45.24 Quite Low
fibrosis 28 39.40 Quite Low
Inflammation 18 27.24 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 156 97.52 Very High Very High Very High
Intestinal Obstruction 1 87.36 High High
Diabetes Mellitus 110 82.24 Quite High
Apoptosis 80 62.96 Quite High
Cicatrix 6 50.16 Quite High
Infection 7 50.00 Quite Low
Adult Respiratory Distress Syndrome 11 46.32 Quite Low
INFLAMMATION 22 44.88 Quite Low
Fibrosis 24 39.40 Quite Low
Pneumoperitoneum 5 25.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrophoretic mobility shift assay (EMSA) was used to determine DNA-binding of nuclear FOXO3a transcription factor.
FOXO3a Binding (binding) of
1) Confidence 0.29 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 0.10 Pain Relevance 0.03
Furthermore, the examination of DNA-bound FOXO3a by electrophoretic mobility-shift assay demonstrated a marked increase in nuclear, DNA bound FOXO3a in GK rats with MI compared to Sham-GK and corresponding post-MI Wistar controls (Figure 5D).


FOXO3a Binding (bound) of associated with myocardial infarction
2) Confidence 0.27 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.72 Pain Relevance 0
Cecum ligation and puncture and treatment with O2 or O2/O3
O3 Binding (ligation) of in puncture
3) Confidence 0.01 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2827707 Disease Relevance 0.09 Pain Relevance 0.13

General Comments

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