INT297962

Context Info Confidence 0.21 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.66 Pain Relevance 0.03

response to stress (MAP3K4, MAPK14) cytoplasm (MAP3K4, MAPK14) cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14) nucleus (MAPK14)

MAP3K4 (Homo sapiens) MAPK14 (Homo sapiens)

Pain Link Frequency Relevance Heat withdrawal 1 69.44 Somatostatin 4 5.00 metalloproteinase 2 5.00 cytokine 2 5.00 Inflammation 2 5.00 alcohol 1 5.00 backache 1 5.00

Disease Link Frequency Relevance Heat Retinoblastoma 6 88.96 Aging 57 65.88 Apoptosis 8 57.88 Necrosis 4 57.36 Cancer 2 9.20 Intervertebral Disk Degeneration 8 5.00 Stress 8 5.00 Shock 4 5.00 Intervertebral Disk Displacement 2 5.00 INFLAMMATION 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Overexpression of GADD45beta has been shown to activate p38 via MTK1 [36-38].

MTK1 Positive_regulation (activate) of p38

1) Confidence 0.21 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.66 Pain Relevance 0.03

General Comments

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