INT297964

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (MAP3K11) nucleoplasm (CDK8) cell death (MAP3K11)
cytoskeleton (MAP3K11) nucleus (CDK8) cytoplasm (MAP3K11)
CDK8 (Homo sapiens)
MAP3K11 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 77.04 Quite High
Inflammation 2 66.28 Quite High
Somatostatin 4 6.40 Low Low
cytokine 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 8 78.88 Quite High
INFLAMMATION 2 66.28 Quite High
Necrosis 4 37.48 Quite Low
Cancer 2 37.12 Quite Low
Shock 4 13.48 Low Low
Aging 57 11.84 Low Low
Intervertebral Disk Degeneration 8 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Retinoblastoma 6 5.00 Very Low Very Low Very Low
Intervertebral Disk Displacement 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three important genes related to cell signaling showed significant downregulation in senescent cells: Mitogen-activated protein kinase 8 interacting protein 2, mitogen-activated protein kinase kinase kinase 11, and mitogen-activated protein kinase 2.
kinase 8 Binding (interacting) of mitogen-activated protein kinase kinase kinase 11
1) Confidence 0.26 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.29 Pain Relevance 0.07

General Comments

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