INT297967

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14)
extracellular region (SCUBE3) nucleus (MAPK14) response to stress (MAPK14)
Anatomy Link Frequency
finger 1
MAPK14 (Homo sapiens)
SCUBE3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 4 96.92 Very High Very High Very High
Inflammation 2 75.76 Quite High
cytokine 2 75.24 Quite High
metalloproteinase 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 57 98.24 Very High Very High Very High
Shock 4 79.12 Quite High
INFLAMMATION 2 75.76 Quite High
Apoptosis 8 73.96 Quite High
Adhesions 1 72.88 Quite High
Stress 8 39.60 Quite Low
Cancer 2 31.84 Quite Low
Necrosis 4 31.36 Quite Low
Intervertebral Disk Degeneration 8 5.00 Very Low Very Low Very Low
Retinoblastoma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several genes related to senescence were found to be significantly upregulated in senescent cells vs. non-senescent cells: p38 (MPAK14), RB-Associated KRAB zinc finger, Discoidin, CUB and LCCL domain, growth arrest and DNA-damage inducible beta, inhibitor of growth family member 5 (p28ING5), sphingosine-1-phosphate receptor 2 and somatostatin receptor 3.
p38 Negative_regulation (inhibitor) of CUB in finger associated with aging and somatostatin
1) Confidence 0.01 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.67 Pain Relevance 0.12

General Comments

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