INT297972

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.67
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MAPK14, ING5) cytosol (MAPK14) nucleoplasm (MAPK14)
signal transduction (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)
Anatomy Link Frequency
finger 2
MAPK14 (Homo sapiens)
ING5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 12 98.32 Very High Very High Very High
cytokine 6 89.08 High High
Inflammation 6 75.76 Quite High
metalloproteinase 6 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
backache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 171 98.24 Very High Very High Very High
Shock 12 82.80 Quite High
INFLAMMATION 6 75.76 Quite High
Apoptosis 24 73.96 Quite High
Adhesions 3 72.88 Quite High
Stress 24 39.60 Quite Low
Cancer 6 34.64 Quite Low
Necrosis 12 34.16 Quite Low
Intervertebral Disk Degeneration 24 5.00 Very Low Very Low Very Low
Retinoblastoma 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several genes related to senescence were found to be significantly upregulated in senescent cells vs. non-senescent cells: p38 (MPAK14), RB-Associated KRAB zinc finger, Discoidin, CUB and LCCL domain, growth arrest and DNA-damage inducible beta, inhibitor of growth family member 5 (p28ING5), sphingosine-1-phosphate receptor 2 and somatostatin receptor 3.
p38 Negative_regulation (inhibitor) of p28ING5 in finger associated with aging and somatostatin
1) Confidence 0.21 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.68 Pain Relevance 0.12
Several genes related to senescence were found to be significantly upregulated in senescent cells vs. non-senescent cells: p38 (MPAK14), RB-Associated KRAB zinc finger, Discoidin, CUB and LCCL domain, growth arrest and DNA-damage inducible beta, inhibitor of growth family member 5 (p28ING5), sphingosine-1-phosphate receptor 2 and somatostatin receptor 3.
p38 Negative_regulation (inhibitor) of growth family member 5 in finger associated with aging and somatostatin
2) Confidence 0.21 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.67 Pain Relevance 0.12
These genes include p38 MAP kinase, discoidin, inhibitor of growth family member 5, and growth arrest and DNA-damage-inducible beta.
p38 MAP kinase Negative_regulation (inhibitor) of growth family member 5
3) Confidence 0.08 Published 2010 Journal BMC Biotechnol Section Abstract Doc Link PMC2828399 Disease Relevance 0.32 Pain Relevance 0.08

General Comments

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