INT298052

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.05
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Cd74) signal transduction (Cd74) extracellular region (Vip)
Golgi apparatus (Cd74) endoplasmic reticulum (Cd74) plasma membrane (Cd74)
Cd74 (Mus musculus)
Vip (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 60 90.40 High High
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 72 95.28 Very High Very High Very High
Pneumonia 78 95.00 High High
Bacterial Meningitis 12 79.36 Quite High
Infection 10 68.64 Quite High
Sepsis 2 67.36 Quite High
Pneumococcal Infection 20 58.44 Quite High
Disease 4 44.16 Quite Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IEDB, RANKPEP, SVMHC, MHCPred, and SYFPEITHI in silico analysis tools revealed peptides in PspA199–246 also interact with a broad range of HLA-DR, -DQ, and -DP allelles.
HLA-DR Binding (interact) of peptides
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2828482 Disease Relevance 0.57 Pain Relevance 0.08
To identify the immunodominant epitopes of PspA, we used in silico MHC affinity measurement methods using both affinity data from the Immune Epitope Database and Analysis Resource (IEDB) [14], eluted peptide data from the SYFPEITHI [12] database as well as RANKPEP [15], SVMHC [16], and MHCPred tools [17], [18], which predicted the PspA peptides that bind HLA-DR, -DQ, and -DP alleles.
HLA-DR Binding (bind) of peptides
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2828482 Disease Relevance 0.48 Pain Relevance 0.05

General Comments

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