INT298196

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (EGFR, PIK3CD) signal transduction (EGFR, PIK3CD) cell differentiation (PIK3CD)
extracellular space (EGFR) nucleus (EGFR) endosome (EGFR)
EGFR (Homo sapiens)
PIK3CD (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 2 74.48 Quite High
COX-2 inhibitor 2 61.12 Quite High
cINOD 6 56.68 Quite High
cytokine 1 34.76 Quite Low
Inflammation 4 34.36 Quite Low
Disease Link Frequency Relevance Heat
Lung Cancer 45 98.68 Very High Very High Very High
Solid Tumor 1 97.72 Very High Very High Very High
Hyperplasia 1 82.88 Quite High
Cancer 6 59.40 Quite High
INFLAMMATION 5 45.32 Quite Low
Immunotherapy Of Cancer 1 14.80 Low Low
Disease 1 9.80 Low Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EGFR appears to be involved in the constitutive activation of the phosphoinositide-3-kinase (PI3/AKT) signalling pathway in MM cell lines and other solid tumors as well as in their resistance to treatment, such as radiation and chemiotherapy [20].
EGFR Positive_regulation (activation) of phosphoinositide-3-kinase associated with lung cancer and solid tumor
1) Confidence 0.04 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2828989 Disease Relevance 0.65 Pain Relevance 0.18

General Comments

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