INT298242

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hist1h3f) molecular_function (Hist1h3f) biological_process (Hist1h3f)
Hist1h3f (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 75 50.00 Quite Low
nociceptor 32 5.00 Very Low Very Low Very Low
calcitonin gene related peptide 11 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
mu opioid receptor 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 4 89.92 High High
Non-small-cell Lung Cancer 2 88.00 High High
Cancer 77 78.92 Quite High
Apoptosis 31 68.24 Quite High
Colon Cancer 4 66.76 Quite High
Solid Tumor 21 62.20 Quite High
Stomach Cancer 36 58.20 Quite High
Ganglion Cysts 85 50.00 Quite Low
Glioblastoma 1 32.24 Quite Low
Toxicity 19 29.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Selection was performed using either a polyclonal rabbit antibody to Brn3a [22] or a polyclonal rabbit antibody to acetylated histone H3 (Upstate Biotechnology/Millipore, Billerica, MA, USA) bound to an anti-rabbit IgG magnetic bead (Invitrogen, Carlsbad CA, USA).
histone H3 Binding (bound) of
1) Confidence 0.10 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0 Pain Relevance 0
The acetylation status of histone H3 in OCUM-2MD3 cells was determined during 48 h of incubation with 1 mM VPA, using an antibody that specifically recognizes hyperacetylated forms of histone H3.
histone H3 Binding (recognizes) of
2) Confidence 0.10 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2994814 Disease Relevance 0.27 Pain Relevance 0
The biological activity of Vorinostat was determined by histone H3 hyperacetylation in PBMC.
histone H3 Spec (determined) Binding (hyperacetylation) of
3) Confidence 0.04 Published 2010 Journal Clinical Epigenetics Section Body Doc Link PMC3020651 Disease Relevance 0.44 Pain Relevance 0

General Comments

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