INT298257

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Proc) extracellular space (Proc) extracellular region (Proc)
nucleus (Pou4f1) DNA binding (Pou4f1)
Pou4f1 (Mus musculus)
Proc (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 75 57.88 Quite High
nociceptor 32 20.64 Low Low
calcitonin gene related peptide 11 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
mu opioid receptor 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 3 100.00 Very High Very High Very High
Targeted Disruption 43 92.92 High High
Herpes Simplex Virus 1 76.40 Quite High
Repression 7 71.44 Quite High
Ganglion Cysts 85 57.88 Quite High
Pain 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, direct regulation has been demonstrated only for bHLH transcription factors that are expressed early in sensory neurogenesis and subsequently repressed by Brn3a [14], and a direct transcriptional activator function has not been demonstrated for Brn3a in vivo.
Brn3a Negative_regulation (repressed) of factors associated with neurodegenerative disease
1) Confidence 0.01 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.54 Pain Relevance 0.03

General Comments

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