INT298265

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Context Info
Confidence 0.61
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk2) cytosol (Ntrk2) plasma membrane (Ntrk2)
nucleus (Runx3) DNA binding (Runx3) kinase activity (Ntrk2)
Runx3 (Mus musculus)
Ntrk2 (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 75 92.08 High High
nociceptor 32 82.72 Quite High
Acute pain 1 13.84 Low Low
calcitonin gene related peptide 11 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
mu opioid receptor 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 85 92.08 High High
Targeted Disruption 43 78.64 Quite High
Pain 3 13.84 Low Low
Nociception 3 10.08 Low Low
Repression 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss of Runx3 may lead to the failure of TrkB and TrkC to segregate into distinct lineages, consistent with previous work demonstrating that Runx3 represses TrkB expression while promoting expression of TrkC [23,44].
Runx3 Negative_regulation (represses) of Gene_expression (expression) of TrkB
1) Confidence 0.61 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.25 Pain Relevance 0.17

General Comments

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