INT298277

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pou4f1, Neurod1) DNA binding (Pou4f1, Neurod1) cell differentiation (Neurod1)
nucleocytoplasmic transport (Neurod1) transcription factor binding (Neurod1) cytoplasm (Neurod1)
Pou4f1 (Mus musculus)
Neurod1 (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 75 99.44 Very High Very High Very High
mu opioid receptor 4 54.24 Quite High
calcitonin gene related peptide 11 50.16 Quite High
nociceptor 32 30.16 Quite Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 85 99.44 Very High Very High Very High
Targeted Disruption 43 95.68 Very High Very High Very High
Repression 7 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brn3a has previously been shown to directly repress the expression of Neurod1 and Neurod4 [14] but an activator function has, to date, only been demonstrated in cell transfection models [21,29].
Brn3a Negative_regulation (repress) of Gene_expression (expression) of Neurod1
1) Confidence 0.58 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.48 Pain Relevance 0.27

General Comments

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