INT298282

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pou4f1, Runx1) DNA binding (Pou4f1, Runx1) transcription factor binding (Runx1)
Pou4f1 (Mus musculus)
Runx1 (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 75 84.80 Quite High
Neuropeptide 4 78.04 Quite High
nociceptor 32 76.00 Quite High
Central nervous system 2 27.96 Quite Low
calcitonin gene related peptide 11 5.00 Very Low Very Low Very Low
mu opioid receptor 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 85 84.80 Quite High
Targeted Disruption 43 63.60 Quite High
Repression 7 47.00 Quite Low
Neurodegenerative Disease 3 15.32 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together these data show that Brn3a creates a permissive condition for the expression of the Runx factors, which then repress TrkB expression and allow differentiation of the principal sensory subtypes.


Brn3a Regulation (condition) of Gene_expression (expression) of Runx
1) Confidence 0.48 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.36 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox