INT298294

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk2) cytosol (Ntrk2) plasma membrane (Ntrk2)
nucleus (Runx3) DNA binding (Runx3) kinase activity (Ntrk2)
Anatomy Link Frequency
neurons 2
Runx3 (Mus musculus)
Ntrk2 (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 32 86.40 High High
trigeminal ganglion 75 65.08 Quite High
calcitonin gene related peptide 11 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
mu opioid receptor 4 5.00 Very Low Very Low Very Low
substance P 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 7 98.72 Very High Very High Very High
Ganglion Cysts 85 65.08 Quite High
Targeted Disruption 43 31.88 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Runx3-/- embryos, TrkC expression is lost, coupled with an increase in TrkB+ neurons, while mis-expression of Runx3 promotes TrkC and represses TrkB [23,34].
Gene_expression (expression) of Runx3 in neurons Negative_regulation (represses) of TrkB
1) Confidence 0.39 Published 2010 Journal Neural Dev Section Body Doc Link PMC2829025 Disease Relevance 0.16 Pain Relevance 0.19

General Comments

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