INT298343

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HES3) DNA binding (HES3) transcription factor binding (HES3)
Anatomy Link Frequency
stem cells 1
HES3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 9 98.64 Very High Very High Very High
cerebral cortex 1 26.40 Quite Low
midbrain 4 20.96 Low Low
Dopamine 5 20.24 Low Low
Spinal cord 1 12.16 Low Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 10 99.96 Very High Very High Very High
Stroke 3 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Post Operative Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, in addition to previously defined self-renewal markers, we used Hes3 expression to assess fast changes in cell state and to determine if Hes3 also recognizes cancer stem cells arising in the CNS.
Hes3 Binding (recognizes) of in stem cells associated with cancer and central nervous system
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2829079 Disease Relevance 0.33 Pain Relevance 0.08

General Comments

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