INT298389

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CYB5B) mitochondrion (CYB5B)
Anatomy Link Frequency
SR-786 1
CYB5B (Homo sapiens)
Pain Link Frequency Relevance Heat
member 8 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Plasmacytoma 2 93.16 High High
Precursor Cell Lymphoblastic Leukemia-lymphoma 2 92.40 High High
Diffuse Large B-cell Lymphoma 8 90.20 High High
Malignant Neoplastic Disease 2 87.92 High High
Hodgkin's Disease 154 87.44 High High
Skin Diseases 2 73.12 Quite High
Lymphadenopathy 2 69.32 Quite High
Anaplastic Large Cell Lymphoma 38 68.04 Quite High
Lymphatic System Cancer 50 63.56 Quite High
Cancer 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible therefore that UHRR contains a relatively high concentration of CYB5B mRNA and, if used as the calibrator, may lead to an underestimation of CYB5B in cell lines such as SR-786 if it has similar levels of the CYB5B mRNA.
Negative_regulation (underestimation) of CYB5B in SR-786
1) Confidence 0.42 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2829491 Disease Relevance 0.90 Pain Relevance 0
Cytoplasmic labelling of CYB5B by mAb R23.1-FITC was blocked by unlabelled mAb R23.1 but not mouse isotype control IgG1 (Figure 15) indicating that this was not a result of non-specific binding of anti-R23.1 to permeabilized cells.


Negative_regulation (blocked) of CYB5B
2) Confidence 0.42 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2829491 Disease Relevance 0.22 Pain Relevance 0

General Comments

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