INT298445

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 5.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (SNAI1) intracellular (SNAI1) cytoplasm (SNAI1)
Anatomy Link Frequency
stroma 4
lymph node 2
SNAI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 14 75.04 Quite High
cytokine 3 26.80 Quite Low
palliative 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 90 100.00 Very High Very High Very High
Cancer 410 99.68 Very High Very High Very High
Apoptosis 71 97.92 Very High Very High Very High
Colon Cancer 44 82.20 Quite High
INFLAMMATION 12 75.04 Quite High
Skin Cancer 60 65.40 Quite High
Recurrence 12 13.84 Low Low
Adhesions 13 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Carcinoma 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the 25 cases classified as "SNAI1-frequent" based on their stroma, 4/25 corresponding tumors were negative, 18/25 had SNAI1 expression in <5% tumors cells and 3/25 were categorized as SNAI1-positive (?
Positive_regulation (had) of Gene_expression (expression) of SNAI1 in stroma associated with cancer
1) Confidence 0.59 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 1.37 Pain Relevance 0
Overall 5/25 (20%) lymph node metastases were SNAI1-positive, 20/25 (80%) had less than 5% SNAI1 expression and none of the metastases was entirely negative for SNAI1.
Positive_regulation (negative) of Gene_expression (expression) of SNAI1 in lymph node associated with metastasis
2) Confidence 0.42 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 1.61 Pain Relevance 0.04
Finally, in the group of cases with "rare/occasional" SNAI1 expression in tumor stroma, 2/15 corresponding tumors were negative, 6/15 had SNAI1 expression in <5% tumors cells and 7/15 were categorized as SNAI1-positive (?
Positive_regulation (had) of Gene_expression (expression) of SNAI1 in stroma associated with cancer
3) Confidence 0.39 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 1.25 Pain Relevance 0
However, we showed that the levels of Snail protein were increased in HCT116 cells treated with IL-1?
Positive_regulation (increased) of Gene_expression (levels) of Snail protein
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908545 Disease Relevance 0.85 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox