INT298454

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Prkcg, Adarb1) nucleus (Prkcg, Adarb1) nucleoplasm (Adarb1)
response to stress (Prkcg) cytoplasm (Prkcg) cytosol (Prkcg)
Anatomy Link Frequency
amygdala 2
Prkcg (Rattus norvegicus)
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 49 100.00 Very High Very High Very High
nMDA receptor 19 100.00 Very High Very High Very High
Spinal cord 5 99.68 Very High Very High Very High
amygdala 87 97.44 Very High Very High Very High
Calcitonin gene-related peptide 103 95.00 High High
nMDA receptor antagonist 6 90.96 High High
Neuronal excitability 9 55.08 Quite High
withdrawal 10 42.96 Quite Low
painful pain 1 41.80 Quite Low
depression 1 31.60 Quite Low
Disease Link Frequency Relevance Heat
Pain 48 100.00 Very High Very High Very High
Nociception 4 60.28 Quite High
Injury 7 40.12 Quite Low
Depression 1 31.60 Quite Low
Anxiety Disorder 1 31.00 Quite Low
Affective Disorder 1 30.36 Quite Low
Neuropathic Pain 3 22.52 Low Low
INFLAMMATION 1 21.68 Low Low
Arthritis 6 5.00 Very Low Very Low Very Low
Headache 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both PKA and PKC contribute to pain-related phosphorylation of NMDA receptors in the spinal cord [63,64] whereas only PKA is involved in the amygdala [26,34].
PKC Positive_regulation (contribute) of Phosphorylation (phosphorylation) of receptors in amygdala associated with pain, nmda receptor, amygdala and spinal cord
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829526 Disease Relevance 0.41 Pain Relevance 1.19

General Comments

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