INT298463

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.77
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Gimap1)
Anatomy Link Frequency
neurons 1
skin 1
Gimap1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
inferior alveolar nerve 302 100.00 Very High Very High Very High
trigeminal ganglion 132 99.76 Very High Very High Very High
Action potential 44 93.72 High High
Neuronal excitability 8 72.08 Quite High
Central nervous system 8 65.76 Quite High
tetrodotoxin 116 63.00 Quite High
hyperexcitability 16 59.68 Quite High
anesthesia 4 55.36 Quite High
halothane 4 52.88 Quite High
fifth nerve 4 34.96 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 138 99.76 Very High Very High Very High
Hypersensitivity 4 99.70 Very High Very High Very High
Nociception 2 66.76 Quite High
Nervous System Injury 34 20.76 Low Low
Pain 20 19.40 Low Low
Congenital Anomalies 4 10.64 Low Low
Neuropathic Pain 16 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Camurati-engelmann Disease 2 5.00 Very Low Very Low Very Low
Headache 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These changes in the physiological properties of TG neurons indicate that the excitability of TG neurons is increased in IAN-transected rats.
Positive_regulation (increased) of IAN-transected in neurons associated with inferior alveolar nerve and trigeminal ganglion
1) Confidence 0.10 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.68 Pain Relevance 1.08
We used IAN-transected rats which showed hypersensitivity to mechanical stimulation of the mental skin and IAN-transected rats without behavior changes which did not show any behavioral changes after IAN transection for single fiber recording experiments.
Positive_regulation (stimulation) of IAN-transected in skin associated with inferior alveolar nerve and hypersensitivity
2) Confidence 0.10 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.10 Pain Relevance 0.64

General Comments

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