INT298465

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 2.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Gimap1)
Anatomy Link Frequency
neuronal 2
skin 2
Gimap1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
inferior alveolar nerve 302 100.00 Very High Very High Very High
Neuronal excitability 8 100.00 Very High Very High Very High
Action potential 44 99.44 Very High Very High Very High
Central nervous system 8 94.96 High High
tetrodotoxin 116 92.20 High High
trigeminal ganglion 132 89.12 High High
hyperexcitability 16 88.88 High High
anesthesia 4 62.88 Quite High
halothane 4 60.40 Quite High
Sciatic nerve 2 56.36 Quite High
Disease Link Frequency Relevance Heat
Hypersensitivity 4 97.42 Very High Very High Very High
Nociception 2 95.96 Very High Very High Very High
Ganglion Cysts 138 89.12 High High
Nervous System Injury 34 49.96 Quite Low
Pain 20 48.60 Quite Low
Neuropathic Pain 16 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Camurati-engelmann Disease 2 5.00 Very Low Very Low Very Low
Headache 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used IAN-transected rats which showed hypersensitivity to mechanical stimulation of the mental skin and IAN-transected rats without behavior changes which did not show any behavioral changes after IAN transection for single fiber recording experiments.
Neg (not) Regulation (changes) of Gene_expression (transection) of IAN in skin associated with inferior alveolar nerve and hypersensitivity
1) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.10 Pain Relevance 0.65
In order to evaluate the changes in neuronal excitability associated with the demonstrated changes in sodium and potassium currents following IAN transection, we analyzed action potentials properties under current-clamp conditions.
Regulation (changes) of Gene_expression (transection) of IAN in neuronal associated with action potential, inferior alveolar nerve and neuronal excitability
2) Confidence 0.09 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.80 Pain Relevance 1.50

General Comments

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