INT298475

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LPA, IL8) transport (LPA) small molecule metabolic process (LPA)
intracellular (IL8) lipid metabolic process (LPA) peptidase activity (LPA)
Anatomy Link Frequency
endothelial cells 2
LPA (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 82 84.20 Quite High
Potency 2 65.52 Quite High
agonist 10 64.36 Quite High
aspirin 5 49.20 Quite Low
Inflammation 38 9.92 Low Low
chemokine 35 5.00 Very Low Very Low Very Low
5HT 23 5.00 Very Low Very Low Very Low
metalloproteinase 15 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
sSRI 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 93 84.20 Quite High
Cancer 4 73.60 Quite High
Metastasis 1 73.04 Quite High
Adhesions 4 71.80 Quite High
Increased Venous Pressure Under Development 2 46.44 Quite Low
Neurological Disease 2 23.64 Low Low
Coagulation Disorder 3 21.76 Low Low
Thrombosis 6 18.96 Low Low
Disease 30 10.28 Low Low
INFLAMMATION 40 9.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lin et al showed that LPA stimulated expression of IL-8 and monocyte chemo-attractant protein-1 (MCP-1) in endothelial cells, in a manner that depended on IL-1 [149].
LPA Positive_regulation (stimulated) of Gene_expression (expression) of IL-8 in endothelial cells
1) Confidence 0.07 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2829540 Disease Relevance 0.38 Pain Relevance 0.15

General Comments

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