INT29856

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Context Info
Confidence 0.38
First Reported 1988
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.24
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ptpn6) phosphatase activity (Ptpn6) cell proliferation (Ptpn6)
nucleus (Ptpn6) cytoplasm (Ptpn6)
Anatomy Link Frequency
eye 2
Ptpn6 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 11 100.00 Very High Very High Very High
Morphine 4 99.32 Very High Very High Very High
ischemia 7 99.20 Very High Very High Very High
analgesia 4 98.96 Very High Very High Very High
opioid receptor 2 89.84 High High
Glutamate 2 27.04 Quite Low
tolerance 1 25.00 Low Low
Opioid 1 25.00 Low Low
tetrodotoxin 36 5.00 Very Low Very Low Very Low
isoflurane 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperglycemia 1 99.76 Very High Very High Very High
Cv Unclassified Under Development 3 99.20 Very High Very High Very High
Diabetes Mellitus 7 92.60 High High
Reperfusion Injury 1 75.00 Quite High
Coronary Artery Disease 4 74.80 Quite High
Vibrio Infection 2 69.28 Quite High
Sprains And Strains 4 53.04 Quite High
Aids-related Complex 6 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, we reported that exogenous administration of Met(5)-enkephalin (ME) for 24 h reduces infarct size after ischemia-reperfusion in rabbits.
Negative_regulation (reduces) of Positive_regulation (administration) of ME associated with ischemia and enkephalin
1) Confidence 0.38 Published 2005 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15550529 Disease Relevance 0.52 Pain Relevance 0.66
ME at P34 did not have an apparent effect upon the size of the CTB-positive area (ME, 13.6±0.5%, n?
Negative_regulation (positive) of Positive_regulation (area) of ME
2) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2882329 Disease Relevance 0 Pain Relevance 0
We tested whether RGCs are still capable of changing their projection patterns in the dLGN in response to ME after eye-specific segregation is mostly complete in mice.
Spec (whether) Negative_regulation (capable) of Positive_regulation (response) of ME in eye
3) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2882329 Disease Relevance 0.12 Pain Relevance 0
Reduction of STZ-induced hyperglycemia by insulin reversed the effectiveness of SC MeNTX in antagonizing morphine analgesia.
Negative_regulation (reversed) of Positive_regulation (effectiveness) of MeNTX associated with hyperglycemia, analgesia and morphine
4) Confidence 0.06 Published 1988 Journal Life Sci. Section Abstract Doc Link 2846978 Disease Relevance 0.60 Pain Relevance 0.81

General Comments

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