INT298569

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.97
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (LILRB1) plasma membrane (LILRB1) cytoplasm (LILRB1)
Anatomy Link Frequency
mammary glands 1
LILRB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 31 97.36 Very High Very High Very High
Inflammatory response 26 50.00 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 207 100.00 Very High Very High Very High
INFLAMMATION 60 97.36 Very High Very High Very High
Reprotox - General 1 20 88.00 High High
Neuroblastoma 6 87.32 High High
Death 17 83.64 Quite High
Cancer 47 59.68 Quite High
Disease 12 52.44 Quite High
Necrosis 23 50.84 Quite High
Colon Cancer 86 50.00 Quite Low
Repression 6 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the up-regulation of miR-34a and miR-195 was associated with a down-regulation of BCL2 and SGK1 protein levels, respectively; whereas the down-regulation of miR-193b, miR-221, miR-222 and miR-7 was associated with an up-regulation of MCL1, BCL2L11 (Bim), CDN1B (p 27) and VDAC1 protein levels, respectively (Figure 9A).
Negative_regulation (down-regulation) of miR-7
1) Confidence 0.05 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.42 Pain Relevance 0
Our qRT-PCR results showed that miR-18a, miR-193, miR-221, miR-222 and miR-7 were down-regulated, whereas miR-195, miR-30d and miR-34a were up-regulated in Par-4-transfected cells when compared with empty vector-transfected cells (Figure 8C).
Negative_regulation (down-regulated) of miR-7
2) Confidence 0.05 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2883962 Disease Relevance 0.55 Pain Relevance 0
The relatively low number of apoptotic monocyte-like RESMAC suggests that the major parts of these cells survive, monitoring inflammatory or other danger signals, and phagocytosing the cellular material of sloughed epithelial and other cells from ducts of mammary glands, as we found in our previous study [17].
Negative_regulation (number) of monocyte-like RESMAC in mammary glands associated with inflammation and apoptosis
3) Confidence 0.01 Published 2010 Journal Acta Vet Scand Section Body Doc Link PMC2829577 Disease Relevance 1.00 Pain Relevance 0.05

General Comments

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