INT298589

Context Info Confidence 0.05 First Reported 2009 Last Reported 2009 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

signal transduction (TNFRSF11B, IL1B) extracellular region (TNFRSF11B, IL1B) aging (IL1B) extracellular matrix organization (TNFRSF11B) cell-cell signaling (IL1B) cytosol (IL1B)

TNFRSF11B (Homo sapiens) IL1B (Homo sapiens)

Pain Link Frequency Relevance Heat Snapping jaw 8 5.00 cytokine 6 5.00 Inflammation 6 5.00 Pain 2 5.00 metalloproteinase 1 5.00 Hyperalgesia 1 5.00 Osteoarthritis 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 1 49.12 Temporomandibular Joint Syndrome 8 5.00 INFLAMMATION 6 5.00 Arthropathy 4 5.00 Pain 2 5.00 Hypercalcemia 2 5.00 Hyperalgesia 1 5.00 Osteoporosis 1 5.00 Osteoarthritis 1 5.00 Milium 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

on the expression of OPG and RANKL; whereas it did not affect the IL-1?

OPG Neg (not) Regulation (affect) of IL-1

1) Confidence 0.05 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2829618 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.