INT298639

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GDE1, AKT1) cell differentiation (AKT1) nucleoplasm (AKT1)
transport (AKT1) small molecule metabolic process (AKT1) enzyme binding (AKT1)
Anatomy Link Frequency
plasma cells 1
GDE1 (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 43 81.96 Quite High
Inflammation 24 80.48 Quite High
cytokine 2 50.16 Quite High
antagonist 1 29.12 Quite Low
ischemia 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Myeloma 53 98.96 Very High Very High Very High
Repression 4 87.12 High High
Cancer 147 83.92 Quite High
INFLAMMATION 27 80.48 Quite High
Epstein-barr Virus 1 75.44 Quite High
Hematologic Neoplasms 39 50.00 Quite Low
Apoptosis 27 45.68 Quite Low
Lymphatic System Cancer 15 5.00 Very Low Very Low Very Low
Metastasis 14 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both miR-15a and miR-16 regulate proliferation and growth of plasma cells by inhibiting Akt and MAPK cell survival signaling pathways.
miR-16 Negative_regulation (inhibiting) of Akt in plasma cells
1) Confidence 0.00 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 1.14 Pain Relevance 0.14

General Comments

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