INT298653

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (EP300) transferase activity, transferring acyl groups (EP300) DNA binding (EP300)
cytoplasm (EP300) nucleolus (EP300) nucleus (EP300)
Anatomy Link Frequency
B cells 2
EP300 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 43 89.44 High High
antagonist 1 72.84 Quite High
cytokine 2 62.20 Quite High
Inflammation 24 14.48 Low Low
ischemia 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Lymphoid Leukemia 7 96.20 Very High Very High Very High
Hematologic Neoplasms 39 77.12 Quite High
Cancer 147 73.80 Quite High
Multiple Myeloma 53 73.56 Quite High
Metabolic Syndrome 7 59.36 Quite High
Body Weight 1 54.88 Quite High
Repression 4 43.80 Quite Low
Obesity 3 24.40 Low Low
INFLAMMATION 27 14.48 Low Low
Epstein-barr Virus 1 9.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
forms an active complex with the transcriptional coactivator p300 and activated Stat3 on the VEGF promoter, which likely explains the anomalous autocrine VEGF secretion from CLL B cells [273].
Positive_regulation (activated) of p300 Binding (complex) of in B cells associated with chronic lymphoid leukemia
1) Confidence 0.11 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.80 Pain Relevance 0.15

General Comments

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