INT298697

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.85
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Tek) kinase activity (Tek)
Anatomy Link Frequency
eyes 1
Tek (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 82.08 Quite High
cytokine 2 74.88 Quite High
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 68 96.84 Very High Very High Very High
INFLAMMATION 11 82.08 Quite High
Corneal Disease 4 76.96 Quite High
Injury 6 75.36 Quite High
Infection 5 55.52 Quite High
Adhesions 11 50.00 Quite Low
Metastasis 3 21.68 Low Low
Solid Tumor 1 19.52 Low Low
Glioblastoma 10 18.40 Low Low
Glioma 47 13.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At day 7 after corneal NV induction and the start of gene therapy, the inhibitory effect of combined mEndo, msFlk-1, or msTie2 gene therapy was obvious when compared to eyes treated with the vehicle vector or saline (Figure 2, Table 1).
Negative_regulation (effect) of msTie2 gene in eyes
1) Confidence 0.35 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2830023 Disease Relevance 0.41 Pain Relevance 0.14
Similar to our in vitro results VEGF, Tie2 and Ang1 were also downregulated under in vivo conditions (Figure 6E).
Negative_regulation (downregulated) of Tie2
2) Confidence 0.08 Published 2010 Journal Aging (Albany NY) Section Body Doc Link PMC3006022 Disease Relevance 0.44 Pain Relevance 0

General Comments

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