INT298716

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ngf, PDGFA) extracellular region (Ngf, PDGFA) signal transduction (Ngf)
aging (Ngf) embryo development (PDGFA) molecular_function (Ngf)
Anatomy Link Frequency
respiratory 2
Ngf (Rattus norvegicus)
PDGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 98.94 Very High Very High Very High
Inflammation 12 98.74 Very High Very High Very High
Kinase C 1 92.52 High High
Pain 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 98.74 Very High Very High Very High
Apoptosis 2 66.16 Quite High
Shock 2 59.28 Quite High
Confusion 1 48.16 Quite Low
Wound Healing 5 30.24 Quite Low
Alopecia 1 26.72 Quite Low
Pulmonary Disease 17 5.00 Very Low Very Low Very Low
Injury 14 5.00 Very Low Very Low Very Low
Stroke 6 5.00 Very Low Very Low Very Low
Ulcers 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These include augmentation of cellular ATP levels [29], manipulation of inducible nitric oxide synthase (iNOS) activity [30,31], suppression of inflammatory cytokines such as TNF-alpha, IL-1beta, IL-6 and IL-8 [32-36], upregulation of growth factor production such as PDGF, IGF-1, NGF and FGF-2 [36-39], alteration of mitochondrial membrane potential [29,40-42] due to chromophores found in the mitochondrial respiratory chain [43,44] as reviewed in [45], stimulation of protein kinase C (PKC) activation [46], manipulation of NF-?
NGF Positive_regulation (upregulation) of Gene_expression (production) of PDGF in respiratory associated with kinase c, inflammation and cytokine
1) Confidence 0.01 Published 2010 Journal J Transl Med Section Body Doc Link PMC2830167 Disease Relevance 0.22 Pain Relevance 0.15

General Comments

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